Apolipoprotein E–Deficient Mice Develop an Anti–Chlamydophila pneumoniaeT Helper 2 Response and Resist Vascular Infection
نویسندگان
چکیده
منابع مشابه
Apolipoprotein E-deficient mice develop an anti-Chlamydophila pneumoniae T helper 2 response and resist vascular infection.
BACKGROUND Hypercholesterolemia could inhibit the immune response against various pathogens. No information is available about its impact on the immune response toward Chlamydophila pneumoniae. METHODS Apolipoprotein E (apoE)-deficient and wild-type mice fed a normal diet were infected with a single intranasal inoculation of viable C. pneumoniae. RESULTS Whereas interferon gamma concentrati...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2010
ISSN: 0022-1899,1537-6613
DOI: 10.1086/655700